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How Amanda Knox Show Compares to Meredith Kercher Murder Trial

Connie Marie by Connie Marie
August 20, 2025
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How Amanda Knox Show Compares to Meredith Kercher Murder Trial
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Hulu went out of their way to transform Tell Me Lies‘ Grace Van Patten into Amanda Knox — but how does the show compare to Meredith Kercher‘s actual murder trial?

The Twisted Tale of Amanda Knox, which premiered on August 20, is a limited series inspired by the story of how Knox “was wrongfully convicted for the tragic murder of her roommate, Meredith Kercher, and her 16-year odyssey to set herself free.” In addition to Patten, the show also stars Sharon Horgan, John Hoogenakker, Francesco Acquaroli, Giuseppe De Domenico and Roberta Mattei.

Knox made headlines in 2007 when she was accused of murdering her roommate Kercher while they were studying abroad in Perugia, Italy. Knox was sentenced to 26 years in prison after she and then-boyfriend Raffaele Sollecito were both convicted of the crime despite a lack of evidence.

An appellate court later found the former couple not guilty in 2011, but they were again found guilty three years later during a retrial. The Italian supreme court cleared Knox of Kercher’s murder in 2015 and she was exonerated.

Ivorian migrant Rudy Guede was sentenced in 2008 to 30 years in prison for Kercher’s murder after his DNA was identified at the crime scene. His sentence was later reduced, and he was released from prison in November 2021.

Before The Twisted Tale of Amanda Knox premiered, Knox spoke exclusively to Us Weekly about her “gratitude” for the chance to tell her story.

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“It really comes down to this idea of do I have a voice and does my voice matter in how a story is told? That is what Hulu has recognized, and they’re taking a chance on that to say, ‘Yes, actually the subject does have a perspective that is valuable and that matters,’” she noted in March 2025. “And we don’t have to pretend that this world is full of objective screenwriters who are not bringing their own stuff to the project. I think that that’s a really interesting experiment that is being made right now.”

She continued: “And of course, I’m really honored to work alongside Monica [Lewinsky], who is my mentor. She’s executive producing as well. I can’t speak a lot about it yet because we’re still in production. But I’ll just say that it is another manifestation of me having the opportunity to be recognized as someone who has a valuable perspective.”

Keep scrolling to see how the series compares to the real-life case:



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Connie Marie

Connie Marie

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